The LFA Nürburgring Edition is a competition-focused variant and was available in four exterior colours, namely glossy black, matte black, race yellow, and whitest white. The production totals are to be included in the 500-unit total LFA planned build cycle, and although Lexus stated it would be limited to a 50-unit run, a total of 64 were produced. Buyers received training sessions at the Nordschleife, accompanied by Nürburgring chief instructors, a one-night stay at the Lindner Congress and Motorsport Hotel Nürburgring, admission to the ring°werk leisure park, a Nürburgring branded jacket, and a one-year pass to the circuit.

The LFA Nürburgring Edition features an extra 7.4 kW (10 PS; 10 hp) from its V10 engine, bringing the total to 420 kW (571 PS; 563 hp). It also features a re-calibrated transmission with gear shifts made faster by 0.05 seconds, a front splitter, stiffer and more adjustable suspension, lightweight alloy wheels wrapped in high performance street tyres, aerodynamic canards at the sides of the front bumper, and a large fixed rear wing.